MVPRE 3.0

The Formula Has More Than One Job

A demanding session calls for blood flow to working muscles, the capacity to sustain hard contractions and the focus to execute the next set. We built MVPRE 3.0 to bring those priorities together: a substantial pump foundation, endurance and strength support, and our high-stimulant Cogni-Stim Matrix. From first-set drive to the adaptations you build over time, every part has a purpose.†

Each full serving delivers 10 g L-Citrulline, 3.2 g Beta-Alanine, 2.5 g Betaine Anhydrous, 100 mg S7® and our 2.8 g Cogni-Stim Matrix, including 350 mg Caffeine. Niacin and Vitamin B12 complete the formula. Every container provides 20 full servings.

Caffeine brings alertness and training drive to the session ahead. Beta-Alanine builds muscle Carnosine with repeated intake, supporting your buffering capacity over time. Betaine adds cellular hydration and strength support, with research typically examining consistent daily use. Together, these ingredients connect the workout in front of you with the progress you are working toward.†

L-Citrulline · 10 g of Pure Pump Support

We start with a massive 10,000 mg of pure L-Citrulline. Every gram contributes to the amino acid foundation of the pump formula. Citrulline Malate includes both Citrulline and Malate: for comparison, 8 g at a verified 2:1 ratio supplies approximately 5.3 g Citrulline. MVPRE 3.0 delivers a full 10 g of L-Citrulline itself.

L-Citrulline is converted into L-Arginine, largely in the kidneys. Arginine is then used by nitric oxide synthase enzymes to produce nitric oxide, a signaling molecule involved in relaxing blood-vessel smooth muscle. This is the physiological foundation of the pump-support story: improve the availability of a precursor used in the body’s own blood-flow signaling system. Citrulline also participates in the urea cycle, which handles nitrogen metabolism.

We chose Citrulline for its ability to raise circulating Arginine, the precursor used in nitric oxide production. Oral Arginine undergoes substantial metabolism before reaching circulation, while human pharmacokinetic research shows that Citrulline effectively increases Arginine availability. The Citrudose study examined 2, 5, 10 and 15 g in eight healthy men and documented dose-related amino-acid responses, with the Arginine response leveling at the highest intakes. This research helps explain the pathway behind our pump foundation.

Ten grams of pure L-Citrulline anchors MVPRE 3.0’s support for blood flow and the full muscular pump you train for. We pair that substantial amino acid foundation with S7® for a complementary approach to nitric oxide support.†

S7® · A Complementary Nitric Oxide Approach

S7® adds a plant-based dimension to our pump strategy. Each serving provides 100 mg of this blend of Green Coffee Bean, Green Tea, Turmeric, Tart Cherry, Blueberry, Broccoli and Kale. Its polyphenol-rich composition has been studied for nitric oxide availability and oxidative balance, complementing Citrulline’s role as an Arginine precursor.†

Nitric oxide availability depends on more than supplying its building blocks. Oxidative balance also matters: excessive reactive oxygen species can interfere with nitric oxide signaling. S7® brings plant compounds studied for supporting that balance, giving our formula another way to support the blood-flow pathways involved in your pump.†

In a randomized, double-blind, placebo-controlled study, 42 overweight or slightly obese adults took 25 mg S7®, 50 mg S7® or placebo daily for 90 days. The S7® groups showed increased circulating nitric oxide bound to Hemoglobin and reduced mitochondrial reactive oxygen species. The reported nitric oxide increases were approximately 34% and 53% at the two studied doses. These measurements highlight S7®’s potential to support nitric oxide availability over consistent use.

We include 100 mg S7® per full serving to bring this plant-based nitric oxide approach alongside 10 g L-Citrulline. One supplies an Arginine precursor; the other supports the oxidative environment around nitric oxide signaling. It is a purposeful pairing for a formula built around powerful pumps.†

Beta-Alanine · Build Your Buffering Capacity

Beta-Alanine’s main training role starts inside the muscle. It combines with Histidine to form Carnosine, and Beta-Alanine availability is a limiting factor in that process. Carnosine helps buffer hydrogen ions during intense exercise. When repeated hard contractions challenge acid-base balance, that buffering system is one contributor to the muscle’s ability to sustain the work.

Each full serving delivers 3.2 g Beta-Alanine. In an early human study, 3.2 g daily for four weeks, divided into smaller doses, increased muscle Carnosine by approximately 42%. The same study also investigated 6.4 g daily. The connection for your training is clear: consistent Beta-Alanine intake helps build the muscle-buffering system you rely on when the work gets intense.†

The ISSN position stand highlights sustained high-intensity efforts, particularly those lasting roughly one to four minutes. That makes Carnosine buffering relevant to demanding intervals and sustained hard work. For athletes pursuing more productive high-intensity training, Beta-Alanine helps support the capacity to keep pushing.†

Think of Beta-Alanine as support you build over time. The temporary tingling some people feel comes from sensory pathways in the skin; muscle Carnosine develops through repeated intake. Use MVPRE 3.0 before training as directed, with no extra scoops or rest-day servings to pursue a loading schedule.†

Betaine Anhydrous · Support Strength & Cellular Hydration

Betaine Anhydrous, also called Trimethylglycine, supports training from inside the cell. As an osmolyte, it helps cells manage water balance and osmotic stress. As a methyl donor, it participates in the conversion of Homocysteine to Methionine, connecting it with nutrient metabolism. These complementary roles make Betaine a purposeful addition for demanding strength training.†

Our 2.5 g serving matches a commonly studied daily amount. In a six-week controlled trial, 23 experienced strength-trained men took 2.5 g daily alongside a periodized training program. Researchers reported improvements in selected body-composition measures and bench-press training volume, highlighting the potential to support productive work over a training block.

A 2024 meta-analysis pooled 17 studies with 317 participants and found that repeated Betaine supplementation improved maximal strength overall, particularly lower-body strength. A sensitivity analysis also identified potential benefits for vertical-jump performance. These findings support Betaine’s place in a formula for athletes pursuing stronger, more explosive training.†

Cellular hydration and methylation support make Betaine part of the formula’s longer-term performance foundation. Pair consistent training with sufficient fluids, nutrition and recovery to put that support to work. The goal is simple: build the conditions for stronger sessions and continued progress.†

Cogni-Stim Matrix · Get Dialed In

The 2.8 g Cogni-Stim Matrix is the formula’s energy-and-focus component. It brings together Caffeine Anhydrous, Choline Bitartrate, N-Acetyl L-Tyrosine, N-Phenethyldimethylamine Citrate from Eria Jarensis, Huperzia Serrata Extract, and Juglandis (Walnut) Powder (Juglans Regia). The goal is a workout you can approach with drive, attention, and intent.†

Our Cogni-Stim Matrix includes 350 mg Caffeine within its 2.8 g total, alongside ingredients selected for complementary roles in neurotransmitter pathways and mental engagement. We designed this blend to bring drive and attention together, helping you approach demanding training with intent.†

Caffeine Anhydrous · 350 mg of High-Impact Energy

Caffeine Anhydrous brings high-impact energy to MVPRE 3.0. By blocking Adenosine receptors, Caffeine helps reduce perceived fatigue and supports alertness. Exercise research connects it with endurance, attention and the ability to maintain effort—useful advantages when you want to show up switched on and stay engaged with the session.†

The ISSN position stand reports exercise benefits commonly at 3–6 mg per kilogram of body mass. Our full serving contains 350 mg Caffeine; a half serving provides 175 mg. Start with half a scoop to assess tolerance and never exceed one scoop in 24 hours.

Plan your pre-workout around the session and the recovery that follows. Assess tolerance with half a scoop, allow enough time before bedtime, and avoid coffee, energy drinks, alcohol and other Caffeine or stimulant products. Protecting sleep helps you bring the same intent to your next workout.

Choline Bitartrate · The Cholinergic Foundation

Choline helps your body make Acetylcholine, a neurotransmitter involved in attention, memory and communication between nerves and muscles. It also contributes to cell-membrane Phospholipids. We use Choline Bitartrate to supply this nutrient within our focus-oriented Cogni-Stim Matrix.†

Human research has explored Choline Bitartrate in tasks that connect attention with movement. A small controlled study using 2 g reported improved visuomotor accuracy in healthy adults. That task-specific finding complements the broader nutritional role of Choline in nerve signaling and motor communication.

Choline Bitartrate contributes the nutritional building blocks for Acetylcholine, while Caffeine supports alertness and training drive. This combination of nutrient support and stimulation is part of how we built the Cogni-Stim Matrix to help you get dialed in.†

N-Acetyl L-Tyrosine · Support the Focus Pathway

Tyrosine is a precursor for Catecholamines, including Dopamine and Norepinephrine, which participate in attention and the response to demanding situations. We include a Tyrosine source as part of the Cogni-Stim Matrix’s focus foundation, supporting the formula’s purpose of helping you stay engaged with the work.†

We use N-Acetyl L-Tyrosine, the acetylated form of Tyrosine, within our proprietary matrix. Its place in the formula centers on the Catecholamine pathway and the nutritional foundation behind focus. Alongside Choline Bitartrate and Caffeine, it contributes to a blend designed for mentally demanding sessions.†

Huperzia Serrata Extract · A Distinct Cholinergic Pathway

We use Huperzia Serrata Extract standardized to 1% Huperzine A. Huperzine A has been studied for inhibiting Acetylcholinesterase, the enzyme that breaks down Acetylcholine. This complements Choline’s role in supplying the building blocks for that neurotransmitter, bringing another pathway into our focus-oriented matrix.

The formulation goal is to support the Acetylcholine side of mental engagement alongside Caffeine’s alertness benefits. Because Huperzia affects cholinergic signaling, review overlapping focus ingredients before combining supplements, particularly other Huperzine A products.

Eria Jarensis · Part of Our Cogni-Stim Blend

Our proprietary Cogni-Stim Matrix includes N-Phenethyldimethylamine Citrate from Eria Jarensis as part of its energy-and-focus profile. We build that experience around 350 mg Caffeine, with supporting ingredients selected to complement the blend’s purpose: helping you bring drive, attention and intent to the workout.†

The Cogni-Stim Matrix also includes Juglandis (Walnut) Powder (Juglans Regia). Contains Walnut.

Niacin · Support the Cellular Energy Machinery

Niacin, or Vitamin B3, helps form NAD and NADP, coenzymes involved in cellular metabolism. These reactions help transfer energy from Carbohydrates, Fats and Proteins into the systems that generate ATP. We include Niacin to support the cellular energy machinery behind an active training routine.†

Each full serving supplies 15 mg NE of Niacin. Nicotinic Acid can cause warmth, redness, itching or flushing, particularly at higher intakes; Beta-Alanine can cause a separate temporary tingling sensation. Our reason for including Niacin is its role in energy metabolism.†

Vitamin B12 · Metabolism, Nerves & Red Blood Cells

We supply 1,000 mcg Vitamin B12 as Methylcobalamin, a metabolically active form. B12 supports nervous-system function, red blood cell formation and DNA synthesis. It also acts as a cofactor in reactions involving Methionine and Methylmalonyl-CoA, connecting it with nutrient metabolism.†

Healthy nerve function, red blood cell formation and nutrient metabolism are foundations for an active lifestyle. Methylcobalamin brings purposeful nutritional support alongside our pump, performance and energy ingredients, rounding out a formula built for serious training.†

Put the Formula to Work

Mix one scoop with 10–16 fl oz water and take 15–30 minutes before exercise. First-time users should begin with half a scoop to assess tolerance. Do not exceed one scoop in 24 hours. Scoop weight and flavoring ingredients vary by flavor; use the serving weight printed on your tub and review its complete directions and warnings.

For a complementary routine with stimulant-free Novapump or Novapump Neuro, review every overlapping ingredient and the total amount. Use reduced servings and take particular care with shared cognitive ingredients. Do not take full servings of both together, and never combine MVPRE 3.0 with another stimulant-based product or additional Caffeine.

Pair MVPRE 3.0 with progressive training, sufficient food and protein, steady hydration and restorative sleep. Bring the drive to today’s session, put the pump and performance support to work, and give consistent training the opportunity to build progress.†

Read the Full Warnings

For healthy adults 18+. Do not use if pregnant or nursing. Consult a qualified healthcare professional before use if you have a medical condition, take prescription or over-the-counter medications, or are planning surgery. Contains Walnut. Too much Caffeine may cause nervousness, irritability, sleeplessness, and rapid heartbeat. Discontinue use and seek medical attention if you experience an adverse reaction. Do not use if the safety seal is broken or missing. Keep out of reach of children. Store in a cool, dry place.