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Genesis-1

BUILT FOR THE LONG RUN.

4.9 · 53 Reviews

Peptide science. Everyday recovery. Genesis-1 features Humanofort™, a naturally derived peptide complex studied for adrenal and endocrine function, cortisol balance, and lipid metabolism. Support recovery today and vitality for the long run.†

Naturally Derived Peptide Complex / 150 mg Per Capsule / 300 mg Per Day / 56 Capsules

$74.99
Two active adults taking a relaxed walk on a coastal trail at sunrise
MAKE RECOVERY PART OF THE PLAN

Built for your daily routine.

Adrenal Support. A More Resilient Stress Response.

Training, work, and everyday pressure all draw on your recovery resources. Humanofort has been studied for changes in cortisol and other endocrine markers. Genesis-1 brings that research into a daily routine focused on healthy adrenal function, hormonal balance, and a resilient response to stress.†

Recovery For The Work You Want To Keep Doing

Recovery is bigger than a day away from the gym. Muscles, tendons, ligaments, and the connective tissues around your joints all belong in the plan. Genesis-1 brings a naturally derived peptide complex to a routine built around productive training, enough protein, and restorative rest. Think longevity: staying strong, active, and ready for the years ahead.†

Vitality For Men & Women

Healthy endocrine function matters for both men and women. The adrenal glands are part of that system, helping coordinate stress responses and hormone production. Genesis-1 centers on supporting balance, daily vitality, and the resilience to keep showing up.†

A Foundation For More Restorative Sleep

Healthy adrenal function and cortisol rhythms are part of the foundation for restful sleep. Genesis-1’s focus on stress-response support fits an evening routine aimed at deeper, more restorative rest. Pair your evening capsule with a consistent bedtime and time to decompress.†

Naturally Derived. Made For Oral Use.

Humanofort comes from fertilized, partially incubated chicken eggs and is purified into a peptide-containing complex. The science starts with a natural source and an oral format studied in humans.†

Cardiovascular Health. Part Of The Long Game.

Humanofort’s human research has explored lipid metabolism, including cholesterol and cardiovascular risk markers. That gives Genesis-1 a heart-health dimension worth exploring alongside its recovery and endocrine-support focus. Read the deep dive for the study details.†

Joints, Tendons & Connective Tissue

Muscles don’t work alone. Research on connective tissue growth factor (CTGF) explores the signals involved in collagen organization and tendon remodeling. That is why joint health and connective-tissue resilience belong in the peptide conversation, alongside muscle recovery. Explore the deep dive for the science behind this area of interest.†

Bioregulation & Healthy Aging

Healthy aging depends on how well your body coordinates its everyday work. Bioregulation is the signaling behind that coordination—from stress responses and metabolism to tissue maintenance. Humanofort research explores adaptive endocrine responses, bringing a balance-focused perspective to Genesis-1’s recovery and longevity story. Explore the deep dive to connect the dots.†

Inside the formula.

Humanofort™ Naturally Derived Peptide Complex150 mg / Capsule

The heart of Genesis-1: a naturally derived extract from fertilized, partially incubated chicken eggs, standardized to F-1 and F-2 fractions. Humanofort’s extraction history is linked to Romanian patent 112102; purification is central to the peptide complex. Its oral research explores adrenal and endocrine responses, cortisol, and lipid metabolism. One capsule provides 150 mg; morning and evening capsules provide 300 mg daily.†

The Peptide MatrixWithin Humanofort™

This peptide complex brings together peptide fractions rather than one isolated, sequence-defined peptide. Historical Humanofort research describes fractions around 5 and 10 kilodaltons. Those molecular sizes help explain the interest in purification, signaling, and oral delivery.†

Growth-Factor ScienceExplore the deep dive

The recovery conversation goes beyond muscle. Growth-factor biology includes IGF signaling in growth and metabolism, CTGF in connective-tissue remodeling, EGF in skin biology, and NGF in nerve-cell function. Humanofort research discusses growth-factor-like activity. Explore the deep dive for the pathways and experimental settings behind this broader recovery story.†

Per capsule: 150 mg. Bottle: 56 capsules / 56 one-capsule servings. Suggested daily routine: 1 capsule in the morning and 1 in the evening. Contains egg.

PEPTIDES, WITHOUT THE GUESSWORK

The naturally derived peptide advantage.

Explore the science behind this naturally derived peptide complex: patented extraction history, oral delivery, adrenal and endocrine support, cortisol, cardiovascular markers, muscle recovery, joint-health potential, connective tissue, and healthy aging.†

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Common Questions

Before you take it.

What Exactly Is Genesis-1?

Genesis-1 is a daily capsule supplement featuring Humanofort™, a naturally derived peptide complex sourced from fertilized, partially incubated chicken eggs. It is designed around recovery, adrenal and endocrine support, and daily vitality for men and women.†

How Do I Take It?

Take 1 capsule in the morning and 1 capsule in the evening, or as directed by your healthcare professional. Each capsule provides 150 mg, for 300 mg across your day. A 56-capsule bottle lasts 28 days at this routine.

Should I Take Genesis-1 Daily?

Yes. Build it into your morning and evening routine, including rest days. Consistency gives you the best opportunity to assess how it fits your recovery, stress-support, and vitality goals. A 56-capsule bottle provides 28 days at 2 capsules daily.†

Is It Suitable For Men & Women?

Genesis-1 is intended for adult men and women. Humanofort has been studied in both, with responses influenced by age and starting hormone levels. The goal is healthy balance and daily vitality.†

Is It Taken Orally?

Yes—Genesis-1 is taken by mouth. Humanofort research includes oral supplementation in humans. The deep dive explains why peptide digestion and uptake are part of the research, and how the related patent approaches oral delivery.

Does It Contain Egg?

Yes. Humanofort is derived from chicken eggs. Do not use Genesis-1 if you have an egg allergy. Naturally derived describes its source; it does not mean allergen-free.

When Should I Assess My Routine?

Give the routine consistency. Humanofort studies have used observation periods including 21 and 60 days. Track how you feel alongside sleep, training, and recovery habits rather than expecting an immediate sensation.†

What About Skin, Hair, Tendons & Joints?

The growth-factor conversation extends beyond muscle to connective tissue, skin, and nerve-cell biology. Our deep dive explains CTGF’s role in collagen and tendon research, alongside other signaling pathways. It identifies which findings come from Humanofort research and which come from independent cell or animal experiments, so you can understand the full recovery picture.†

What About Cardiovascular Health?

Humanofort research has reported changes in cholesterol and other cardiovascular risk markers after repeated oral use. It’s a promising part of the ingredient’s healthy-aging story. Read the deep dive for the populations, duration, and findings behind the cardiovascular-support potential.†

How Does Bioregulation Relate To Healthy Aging?

Bioregulation describes how cellular signals and feedback help coordinate stress response, metabolism, and tissue maintenance. These functions matter for staying active and resilient as we age. Humanofort’s older-adult research explored adaptive endocrine and metabolic responses, which is why healthy aging is part of the Genesis-1 story. Explore the deep dive for the connection.†

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For adults. Contains egg. Do not use if pregnant or nursing. If you take medication, have a medical condition, or have a hormone-sensitive condition, seek qualified guidance before use. Keep out of reach of children.

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Genesis-1

The naturally derived peptide advantage.

Natural Origin / Patent Science / Oral Delivery / Adrenal & Endocrine Support / Cortisol / Muscle Recovery / Joints & Connective Tissue / Growth Factors / Cardiovascular Research / Longevity

01. A Naturally Derived Peptide Complex

Peptides are having a moment. The idea behind Genesis-1 has a much longer history: a purified extract from fertilized, partially incubated chicken eggs, developed for oral supplementation. Humanofort is the ingredient at the center of that story. Its natural origin matters because this is a biological mixture, with peptide fractions produced within the source material.

A peptide is a chain of amino acids. Many peptides take part in communication between cells. “Complex” is a useful word here: Humanofort is an extract containing peptide fractions, rather than a single isolated peptide with one defined sequence. That makes its source, processing, and research history central to understanding it.

For your routine, the proposition is straightforward: a naturally derived oral peptide complex, taken daily, with recovery and vitality as the focus. Our longevity mindset is about staying strong, active, and engaged in life over the long run.†

02. Bioregulation, Aging & Your Internal Signals

Bioregulation is the coordination of biological activity through signals and feedback. Hormones and growth factors carry messages; receptors and feedback loops help determine the response. Those conversations connect energy use, adaptation to stress, and tissue maintenance. Homeostasis is the body’s ability to keep these functions within a workable range as demands change.

Humanofort researchers described responses as adaptive-regulatory. In older-adult studies, changes in endocrine and metabolic markers depended on initial values, age, and sex. The scientific interest is a response shaped by the person’s starting state, rather than simply pushing every marker upward. [1,3,5]

This connects bioregulation with healthy aging. Sleep patterns, hormonal rhythms, and recovery demands can change with age. Keeping the body’s signaling and recovery systems in view helps explain why longevity is about maintaining function: staying active, responding to stress, and continuing the everyday processes that support tissue health. [11]

Genesis-1 brings a naturally derived peptide complex to that balance-focused approach. Its ingredient research explores endocrine and metabolic responses; the broader growth-factor literature examines cellular communication. Together, these areas make bioregulation a useful framework for understanding recovery and healthy-aging potential—not a measurement of lifespan extension.†

03. The Patent Story: Protection & Delivery

Humanofort’s original research identifies its extraction procedure with Romanian OSIM patent 112102 (1997). That history concerns how the material is processed into an extract. It is part of what separates the ingredient’s development from an ordinary egg-powder story. [3]

A later, related U.S. patent—US 9,999,654 B2, granted in 2018—addresses oral peptide delivery. It describes releasing growth factors from binding complexes, separating material by molecular size, and combining delivery components intended to reduce digestive breakdown and encourage intestinal uptake. [4]

The later patent describes a broader multi-ingredient formulation; Genesis-1 features the Humanofort complex. The useful takeaway is the engineering question behind this research: how do you preserve access to peptide activity through processing and oral delivery? That is where digestion, protection, and absorption enter the story. [4]

04. Oral Peptides: From Capsule To Research

With any oral peptide, digestion and uptake matter. Large proteins and smaller peptides can behave differently in the digestive tract. Extraction, molecular size, and the surrounding matrix all affect the scientific questions researchers need to ask.

Humanofort has been administered orally in human studies, with changes in blood biomarkers reported after repeated use. That gives its research a practical connection to the capsule format. Their focus is the endocrine and metabolic response after oral supplementation. [1–3]

For you, the format is simple: morning and evening capsules. The delivery research belongs in the explanation of the ingredient, while your routine stays easy to repeat. Genesis-1 brings the oral peptide conversation into a daily supplement habit.†

05. Adrenal Function, Cortisol & Recovery

Your adrenal glands produce cortisol as part of the body’s response to demands. The hypothalamus, pituitary, and adrenals communicate through the HPA axis. This endocrine network helps coordinate stress responses and daily rhythms—making healthy adrenal function part of the recovery conversation.

In a 60-day before-and-after study published in Acta Endocrinologica, 80 adults aged 50–75 took an oral peptide preparation. Researchers reported lower cortisol along with changes in insulin, IGF-1, and lipid markers. Participants served as their own controls, and responses differed by starting status. [1]

That endocrine research is the basis for exploring healthy adrenal function and stress-response support. Genesis-1 fits a recovery plan that also gives your body regular sleep, adequate nutrition, and room between demanding sessions. Put as much intention into coming down from the effort as you put into the effort itself.†

06. Hormonal Health: A Closer Look At The Studies

A Romanian Journal of Biochemistry paper examined Humanofort in 30 male rugby players aged 20–30 over 21 days. There were three groups of ten, including a placebo group. The authors reported increases in testosterone and androstenedione relative to starting values; differences were significant against baseline, with substantial individual variation. [3]

The same paper described an older-adult cohort of 18 men and 22 women using oral Humanofort for 60 days. Hormonal responses varied with age, sex, and initial levels. The investigators tracked hormonal biomarkers to explore adaptive regulation. [3]

That is a compelling reason to keep exploring endocrine balance. It is why Genesis-1 brings recovery, resilience, and vitality together in one daily ritual for men and women.†

07. Vitality, Libido & The Whole Person

Feeling like yourself involves more than a training number. Energy, mood, sexual well-being, and the ability to handle daily demands all sit within a wider picture of health. Hormonal function is one part of that picture; sleep, relationships, nutrition, and stress matter too.

The endocrine research makes vitality an interesting area for Humanofort. The relationship between hormonal function and sexual well-being makes libido an area of potential interest; the Humanofort studies discussed here focus on hormonal biomarkers. For men and women, our emphasis is a steady daily routine that supports the foundations of feeling and performing well.†

Use your own goals to keep the routine grounded. Consistency in training, a better evening routine, and the energy to engage with your day are useful things to pay attention to. They give “daily optimization” a meaning beyond the phrase on the bottle.

08. Rest, Relaxation & The Evening Routine

Recovery needs a place in your calendar. A predictable bedtime, a quieter final hour, and enough time asleep are practical ways to give it that place. Your evening capsule can become a cue to start that routine.

Independent sleep research helps explain the connection. In a controlled crossover experiment in healthy men, two nights with restricted time in bed altered HPA-axis activity and increased evening cortisol compared with longer sleep opportunities. This was a sleep-restriction experiment, separate from Humanofort research. [7]

Healthy cortisol rhythms help connect the demands of the day with the opportunity to rest at night. Supporting stress balance may help create better conditions for unwinding and restorative sleep. That is the connection behind Genesis-1’s evening routine: adrenal and endocrine support alongside the habits that make deeper rest possible.†

09. Strength Starts With A Sustainable Routine

Progress happens across repeated sessions. Training gives the stimulus; food, sleep, and recovery help determine how consistently you can return to it. Genesis-1 is designed to sit in that daily recovery foundation, with the long game in mind.†

There is also laboratory work behind the muscle-signaling interest. A 2010 study screened supplements directly on sheep muscle-derived satellite cells. A Humanofort preparation increased proliferation at one tested dilution, with no significant differentiation effect. This cell-culture finding adds to the scientific interest in muscle signaling. [6]

Make recovery as intentional as your training. Progressive loading, adequate protein, and quality sleep help build a routine you can repeat. Keep muscles, tendons, ligaments, and joint function in view together. Genesis-1 is your daily peptide complex within that bigger recovery plan.†

10. A Field Guide To Growth-Factor Biology

Growth factors are signaling proteins. The Humanofort literature discusses growth-factor-like activity and names IGF, EGF, FGF, and NGF as relevant biological examples. Each name opens a different window into cellular communication. [1,3]

IGF-1 and IGF-2 are associated with growth and metabolic signaling. FGF is a family with roles in tissue development and repair. NGF is linked to the survival and development of certain nerve cells; classic experiments studied those effects directly in cultured neurons. [9]

EGF biology is closely associated with epithelial cells, including skin. CTGF is studied in connective-tissue remodeling. These pathway explanations show the breadth of growth-factor biology. Genesis-1 provides the complete Humanofort complex; the stated dose is the amount of that complex.

11. Recovery Beyond Muscle: Joints & Connective Tissue

Your training is only as repeatable as your recovery plan. Muscles create force; tendons transmit it; ligaments help stabilize joints. These tissues rely on organized collagen and coordinated cellular signals. Joint health and connective-tissue maintenance deserve a place beside muscle in the long-game conversation.

CTGF is one reason growth-factor biology attracts interest here. In a 2015 study, researchers delivered CTGF locally in a rat tendon-injury model and studied tendon-resident cells. They observed aligned collagen and tendon-remodeling responses. This was local experimental delivery, not oral Genesis-1 supplementation. [8]

That research explains the interest in connective-tissue signaling. For your daily routine, the practical priorities are broader: sensible training loads, enough nutrition, restorative rest, and consistent movement. Genesis-1 brings naturally derived peptide science to that recovery-focused approach to staying active.†

12. Skin, Hair & Cellular Renewal

Skin and hair follicles are active tissues, influenced by a network of cellular signals. EGF and IGF signaling are part of that wider biology. Understanding those pathways helps explain why growth factors show up in conversations about skin maintenance and healthy aging.

Hair-follicle signaling is particularly context-dependent. Experiments in isolated human hair follicles show that EGF affects different aspects of follicle development differently. The signal, concentration, tissue, and route all matter. [10]

For Genesis-1, healthy aging is about supporting a durable daily routine and continued vitality. The field of growth-factor biology is fascinating context for that interest. The broader science offers a window into the cellular processes that keep researchers asking new questions about aging and renewal.†

13. Cardiovascular Health: Follow The Lipid Research

Heart health belongs in the long-game conversation. A 2005 preliminary Humanofort study followed 40 adults aged 50–75 for 60 days. Participants served as their own controls. The authors reported lower total and LDL cholesterol, with increased HDL cholesterol and reduced insulin in 80% of participants. Cholesterol/HDL and apolipoprotein B/A ratios shifted favorably. [2]

The 80-person Acta Endocrinologica report also explored lipid and endocrine changes over 60 days. A subsequent paper examined the relationship between IGF-1 and lipid responses, which depended on initial levels. These are ingredient-research findings on biomarkers, rather than a trial of Genesis-1 or a measurement of heart attacks, stroke, or lifespan. [1,5]

Together, these findings make cardiovascular-support potential a meaningful part of the Humanofort story. Genesis-1 fits a healthy-aging routine that also values regular movement, sensible nutrition, and recovery. Longevity starts with the foundations you can keep building every day.†

14. Make It A Daily Ritual

Keep it simple: one capsule in the morning and one in the evening. Each capsule provides 150 mg, for 300 mg across your day. At 56 capsules per bottle, that is 28 days of a consistent routine. Follow the directions on the package you receive.

Rest days count. Recovery and the ordinary demands of life continue between workouts. A morning-and-evening habit makes daily use easier to remember and connects your supplement routine with the parts of the day you already repeat.

Keep expectations connected to habits you can sustain: quality training, enough protein, reliable sleep, and time to decompress. Genesis-1 is built for that long view—a naturally derived peptide complex for a routine centered on recovery, resilience, and vitality.†

Explore the research

Humanofort studies, original patent documents, and independent research on the pathways discussed above. Study populations, formulations, and endpoints are identified in the relevant chapters.

  1. Mihăescu et al. (2005). Oral peptides and endocrine/metabolic markers in 80 older adults. Acta Endocrinologica 1:263–270. ↗
  2. Mihăescu et al. (2005). Humanofort and lipid markers: 40-person preliminary study. PMID 16739873. ↗
  3. Mihăescu et al. (2006–2007). Regulatory modifications of steroidogenesis. Romanian Journal of Biochemistry 43–44:37–43. ↗
  4. U.S. Patent 9,999,654 B2 (2018). Oral peptide composition and preparation process; related delivery research. ↗
  5. Mihăescu et al. (2006). IGF-1 and regulatory changes following peptides. PMID 18386621. ↗
  6. Fernyhough et al. (2010). Nutritional supplements and muscle-derived stem cells in vitro. ↗
  7. Guyon et al. (2014). Sleep restriction and the HPA axis in healthy men. PMID 24823456. ↗
  8. Lee et al. (2015). Local CTGF delivery and tendon regeneration. Journal of Clinical Investigation. ↗
  9. Chun & Patterson (1977). NGF and cultured sympathetic-neuron survival and development. PMID 925075. ↗
  10. Philpott & Kealey (1994). EGF in isolated human hair follicles. PMID 8106747. ↗
  11. Van Cauter et al. (2000). Age-related sleep, growth hormone and cortisol patterns in healthy men. JAMA. PMID 10938176. ↗

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.